$.connection.hub is created in the /signalr/hubs inclusion.
At the end of the file it essentially does:
$.connection.hub = $.hubConnection("/signalr", { useDefaultPath: false });
To create the hub proxy you do:
var myHub = $.connection.hub.createHubProxy('myHub');
Simple example for multiple connections:
var connection1 = $.hubConnection("http://www.myfirstendpoint.com");
var connection2 = $.hubConnection("http://www.mysecondendpoint.com");
var myCon1Hub = connection1.createHubProxy('myCon1Hub');
var myCon2Hub = connection2.createHubProxy('myCon2Hub');
myCon1Hub.client.foo = function() { ... Whatever you want ... };
myCon2Hub.client.foo = function() { ... Whatever you want ... };
connection1.start();
connection2.start();