Let's say you have two models called Store and Product, and it doesn't matter if they're related or not.
On your View you could do this:
echo $this->Form->create('Store');
echo $this->Form->input('Store.name');
echo $this->Form->input('Store.location');
echo $this->Form->input('Product.name');
echo $this->Form->input('Product.type');
echo $this->Form->end('Save');
And on your StoresController you should do this, to save both models data:
// CakePHP 1.3
$this->Store->save($this->data['Store']);
$this->Product->save($this->data['Product']);
// CakePHP 2.0
$this->Store->save($this->request->data['Store']);
$this->Product->save($this->request->data['Product']);
If they're related models, you could save both with one simple call:
$this->Product->saveAll($this->data); // CakePHP 1.3
$this->Product->saveAssociated($this->request->data); // CakePHP 2.0
Do not forget to check the documentation:
CakePHP 1.3 - http://book.cakephp.org/1.3/en/view/1031/Saving-Your-Data
CakePHP 2.0 - http://book.cakephp.org/2.0/en/models/saving-your-data.html#model-saveassociated-array-data-null-array-options-array