I agree with the other answer that once scaling comes into play, an external load balancer in front of NiFi would be helpful.
In regards to the flow design, I would suggest using a single exposed port to ingest all the data, and then use RouteOnAttribute or RouteOnContent processors to direct specific sensor inputs into different flow segments.
One of the strengths of NiFi is the generic nature of flows given sufficient parameterization, so taking advantage of flowfile attributes to handle different data types dynamically scales and performs better than duplicating a lot of flow segments to statically handle slightly differing data.
The performance overhead to run multiple ingestion ports vs. a single port and routed flowfiles is substantial, so this will give you a large performance improvement. You can also organize your flow segments into hierarchical nested groups using the Process Group features, to keep different flow segments cleanly organized and enforce access controls as well.
2020-06-02 Edit to answer questions in comments
Yes, you would have a lot of relationships coming out of the initial RouteOnAttribute processor at the ingestion port. However, you can segment these (route all flowfiles with X attribute in "family" X here, Y here, etc.) and send each to a different process group which encapsulates more specific logic.
Think of it like a physical network: at a large organization, you don't buy 1000 external network connections and hook each individual user's machine directly to the internet. Instead, you obtain one (plus redundancy/backup) large connection to the internet and use a router internally to direct the traffic to the appropriate endpoint. This has management benefits as well as cost, scalability, etc.
The overhead of multiple ingestion ports is that you have additional network requirements (S2S is very efficient when communicating, but there is overhead on a connection basis), multiple ports to be opened and monitored, and CPU to schedule & run each port's ingestion logic.
I've observed this pattern in practice at scale in multinational commercial and government organizations, and the performance improvement was significant when switching to a "single port; route flowfiles" pattern vs. "input port per flow" design. It is possible to accomplish what you want with either design, but I think this will be much more performant and easier to build & maintain.