I suspect it would take an atomic clock to measure the time difference between formatting 151 rows and 150 rows but if you really want to limit the range, while applying whole column references so adding and deleting rows does not fragment the Applies to range, then you could put the restrictions in the formula, if using a formula rule.
For example assuming the requirement is to format the cells in ColumnA containing odd numbers (in Number format) then select ColumnA (for an Applies to range of =$A:$A) and set the formula rule to something like:
=AND(ISODD(A1),ROW()>3,ROW()<155)
My guess is that other changes to your sheet would be a much more effective way to speed up processing (eg INDEX/MATCH can be quicker than VLOOKUP).