Portability (however defined) is not likely to be your primary goal in building an AST. Few (if any) compiler frameworks provide a clear interface which allows the use of an external AST, and particular AST structures tend to be badly-documented and subject to change without notice. (Even if they are well-documented, the complexity of a typical AST implementation is challenging.)
An AST is very tied to the syntactic details of a language, as well as to the particular parsing strategy being used. While it is useful to be able to repurpose ASTs for multiple tasks -- compiling, linting, pretty-printing, interactive editing, static analysis, etc. -- the conflicting demands of these different use cases tends to increase complexity. Particularly at the beginning stages of language development, you'll want to give yourself a lot of scope for rapid prototyping.
The most tempting reason for portable ASTs would be to use some other language as a target, thereby saving the cost of writing code-generation, etc. However, in practice it is usually easier to generate the textual representation of the other language from your own AST than to force your parser to use a foreign AST. Even better is to target a well-documented virtual machine (LLVM, .Net IL, JVM, etc.), which is often not much more work than generating, say, C code.
You might want to take a look at the LLVM Kaleidoscope tutorial (the second section covers ASTs, although implemented in C++). Also, you might find this question on a sister site interesting reading. And finally, if you are going to do your implementation in Javascript, you should at least take a look at the jison parser generator, which takes a lot of the grunt-work out of maintaining a parser and scanner (and thus allows for easier experimentation.)
