I would go with 4 entity types: products, tables, columns, and rows.
The relationship between products and tables is best handled by a :table/product to-one ref attribute, but a :product/tables to-many component ref attribute could also work (the latter does not enforce the one-to-many relationship).
Likewise, I would use either a :column/table or :table/columns attribute. I would also have a :column/name string attribute and maybe a :column/type enumerated attribute.
The hardest part is to model rows.
One tempting solution is to just create an attribute per column - I actually think it's bad idea, Datomic attributes are not intended for such a dynamic use. In particular, schema attributes are stored in a cache on the Peer that's not meant to grow big. (I may be wrong about this, so it'd be nice if someone in the Datomic team could confirm.)
Instead, I would have a few dozens reusable :row/cell-0, :row/cell-1, :row/cell-2, etc. 'cell position' attributes, that are shared across all tables. Each actual column would be mapped to a at creation time by a to-one :column/position attribute.
If the rows can have several data types, it's a bit more difficult, you'd have to basically make an attribute for each (type,position) pair.
Then each row basically consist of a :row/table attribute and the above cell position attributes.
Here's a Datalog query that would let you read the whole table
[:find ?row ?column-name ?val :in $ ?table :where
[?column :column/table ?table]
[?row :row/table ?table]
[?row ?pos ?val]
[?column :column/position ?pos]
[?column :column/name ?column-name]]
Note that all of the above is only useful if you want to query the table with Datalog directly against your Datomic db. But it can be also completely fine to serialize your tables and store them as blobs - especially if they're small; later, you pull out the blob, deserialize it, then you can query with Datalog too. And if tables are to coarse for this use, maybe you can do it with rows.