What you are trying to do is called "function composition". Check out the function composition operator of f#:
I don't have a compiler available to experiment, but you could start from
let otherFunc = myFunc >> not
and work your way through errors.
EDIT: Max Malook points out that this will not work with the current definition of myFunc, because it takes two arguments (in a sense, this is functional-land). So, in order to make this work, myFunc would need to change into accepting a Tuple:
let myFunc (a, b) = a > b
let otherFunc = myFunc >> not
let what = otherFunc (3, 4)