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What would be the best FHIR Resource to represent parameters for a device treatment (treatment duration, blood flow, volume of medication) ? These parameters are Patient dependant. I looked at "Care Plan" and "Procedure" resources, but they don't seem to represent such kind of data. Maybe it is possible using attributes "Timing", "Quantity" and "Details" of Care Plan/Activity relation ?

All answers are welcome.

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Are these independent of a single order? (If order-specific, I'd say MedicationPrescription for most) - Lloyd McKenzie
It's not specific to an order. It's a repetitive daily hemodialysis treatment and the parameters of the treatment could change some days. I was thinking of an "Care-Plan", linked to an hemodialysis "Activity". But the problem is that the Activity detail contains only a 0..1 relation to a "Simple" detail containing two measurables parameters : dailyAmount and quantity, whereas I need many parameters such as blood volume, hemodialysis duration, number of cycles, pressures. That's not only a medication quantity.. How could it be done ? - FhirUser

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Care Plans can have lots of discrete data associated with them, but most of it is relegated to extensions, as few systems support a lot of discrete information. Care Plan sounds like the right solution for your requirement.