It is preferred to aggregate event logs before ingesting them into Amazon Redshift.
The benefits are:
You will use the parallel nature of Redshift better; COPY on a set of larger files in S3 (or from a large DynamoDB table) will be much faster than individual INSERT or COPY of a small file.
You can pre-sort your data (especially if the sorting is based on event time) before loading it into Redshift. This is also improve your load performance and reduce the need for VACUUM of your tables.
You can accumulate your events in several places before aggregating and loading them into Redshift:
Local file to S3 - the most common way is to aggregate your logs on the client/server and every x MB or y minutes upload them to S3. There are many log appenders that are supporting this functionality, and you don't need to make any modifications in the code (for example, FluentD or Log4J). This can be done with container configuration only. The down side is that you risk losing some logs and these local log files can be deleted before the upload.
DynamoDB - as @Swami described, DynamoDB is a very good way to accumulate the events.
Amazon Kinesis - the recently released service is also a good way to stream your events from the various clients and servers to a central location in a fast and reliable way. The events are in order of insertion, which makes it easy to load it later pre-sorted to Redshift. The events are stored in Kinesis for 24 hours, and you can schedule the reading from kinesis and loading to Redshift every hour, for example, for better performance.
Please note that all these services (S3, SQS, DynamoDB and Kinesis) allow you to push the events directly from the end users/devices, without the need to go through a middle web server. This can significantly improve the high availability of your service (how to handle increased load or server failure) and the cost of the system (you only pay for what you use and you don't need to have underutilized servers just for logs).
See for example how you can get temporary security tokens for mobile devices here: http://aws.amazon.com/articles/4611615499399490
Another important set of tools to allow direct interaction with these services are the various SDKs. For example for Java, .NET, JavaScript, iOS and Android.
Regarding the de-duplication requirement; in most of the options above you can do that in the aggregation phase, for example, when you are reading from a Kinesis stream, you can check that you don't have duplications in your events, but analysing a large buffer of events before putting into the data store.
However, you can do this check in Redshift as well. A good practice is to COPY
the data into a staging tables and then SELECT INTO a well organized and sorted table.
Another best practice you can implement is to have a daily (or weekly) table partition. Even if you would like to have one big long events table, but the majority of your queries are running on a single day (the last day, for example), you can create a set of tables with similar structure (events_01012014, events_01022014, events_01032014...). Then you can SELECT INTO ... WHERE date = ...
to each of this tables. When you want to query the data from multiple days, you can use UNION_ALL.