Very likly that mean your dns server was not working. Use local dns caching server or more then one dns server.
Other posible situation - you calling somethign like SIP/1234, which is not in your sip.conf.
Here is related source part, it have description:
peer = sip_find_peer(peername, NULL, TRUE, FINDPEERS, FALSE, 0);
if (peer) {
int res;
if (newdialog) {
set_socket_transport(&dialog->socket, 0);
}
res = create_addr_from_peer(dialog, peer);
dialog->relatedpeer = sip_ref_peer(peer, "create_addr: setting dialog's relatedpeer pointer");
sip_unref_peer(peer, "create_addr: unref peer from sip_find_peer hashtab lookup");
return res;
} else if (ast_check_digits(peername)) {
/* Although an IPv4 hostname *could* be represented as a 32-bit integer, it is uncommon and
* it makes dialing SIP/${EXTEN} for a peer that isn't defined resolve to an IP that is
* almost certainly not intended. It is much better to just reject purely numeric hostnames */
ast_log(LOG_WARNING, "Purely numeric hostname (%s), and not a peer--rejecting!\n", peername);
return -1;
} else {