Seems to me that the problem is equivalent (if you consider each histogram as a N-dimensional vector), to minimizing the Manhattan length |R|, where R=xA-B, A and B are your 'vectors' and x is your proportional scale.
|R| has a single minimum (not necessarily an integer) so you can find it fairly rapidly using a simple bisection algorithm (or something akin to Newton's method).
Then, assuming you want a solution where the proportion is an integer, test the two cases ceil(x), and floor(x), to find which has the smallest Manhattan length (and that is the number of observations you need to remove).
Proof that the problem is not NP-hard:
Consider an inefficient 'solution' whereby you removed all N observations from all the bins. Now both A and B are equal to the 'zero' histogram 0 = (0,0,0,...). The two histograms are equal and thus proportional as 0 = s * 0 for all proportional values s, so a hard maximum for the number of observations to remove is N.
Now assume a more efficient solution exists with assitions/removals < N and a proportional scale s > 2*N (i.e after removal of some observations A = N * B or B=N * A ). If both A = 0 and B = 0, we have the previous solution with N removals (which contradicts the assumption that there are less than N removals). If A = 0 and B ≠ 0 then there is no s <> 0 such that 0 = s * B and no s such that s * 0 = B (with a similar argument for B = 0 and S ≠ 0). So it must be the case that both A ≠ 0 and B ≠ 0. Assume for a moment that A is the histogram to be scaled (so A * s = B), A must have at least one non-zero entry A[i] with minimum value 1 (after removal of extra observations), so when scaled it will have minimum value ≥. Therefore the equivalent entry B[i] must also have at least 2*N observations. But the total number of observations was initially N, so we have needed to add at least N observations to B[i], which contradicts the assumption that the improved solution had less than N additions/removals. So no 'efficient' solution requires a proportional scale greater than N.
So to find an efficient solution requires, at worst, testing the 'best fit' solution for scaling factors in the range 0-N.
The 'best fit' solution for scaling factor s in A = s * B, where A and B have M bins each requires
Sum(i=1 to M) of { Abs(A[i]- s * B[i]) mod s + Abs(A[i]- s * B[i]) div s } additions/removals.
This is an order M operation, so to test for each scaling factor in the range 0-N will be an algorithm of order O(M*N)
I am fairly certain (but haven't got a formal proof), that the scale factor cannot exceed the number of observations in the most filled bin. In practice it is typically very much smaller. For two histograms with two hundred bins and randomly chosen 30-300 observations per bin: if there were Na > Nb total observations in all the bins of A and B respectively the scaling factor was either almost always found in the range Na/Nb-4 < s < Na/Nb + 4, (or s = 0 if Na >> Nb).
