Thanks again to Jan for responsing
After reviewing the SysDataExcelCOM class, there is a CreateWorkbook method which creates the additional worksheets for the Excel Data Definition export. After creating a new similar class method and also declaring my own set of defined names (#define.ExampleExcelWorksheetName('abcSheet') for the Excel Worksheets, I was then able to create the Excel Workbook with multiple worksheets. Then save (SysExcelWorkbook.saveAs) after all of the necessary sheets are created first, rather than open the saved Workboook then adding worksheets per new class method.
Within the other class methods where data is intended to write to the Worksheets, I opened the Workbook created by the new method similar to CreateWorkbook (sysExcelWorkbooks.open(yourExcelFile), then refer to each Worksheet using (sysExcelWorksheet.itemByName) to write the data to the specific Worksheet, then save.
excelApplication = SysExcelApplication::construct();
excelWorkbooks = excelApplication.workbooks();
excelWorkbooks.open(fileNameSave);
excelWorkbook = excelWorkbooks.item(1);
//Add styles and fonts
excelStyles = excelWorkbook.styles();
excelStyle = excelStyles.add("Header");
excelFont = excelStyle.font();
excelFont.bold(true);
excelWorksheets = excelWorkbook.worksheets();
excelWorksheet = excelWorksheets.itemFromName(#declared name of your worksheet);
// Begin Header Row
excelWorksheet.cells().item(1,1).value("value of your choice");
excelWorksheet.cells().item(1,2).value("value of your choice");
excelWorksheet.rows().item(1).style("Header");
excelWorksheet.name("Rename your declared worksheet name or use current name here");
excelCells = excelWorksheet.cells();
excelCells.range('A:B').numberFormat('@');
//Find you data to write to Excel Worksheet here
excelWorksheet.columns().autoFit();
excelApplication.displayAlerts(false);
excelWorkbook.saveAs(fileNameSave);
excelWorkbook.comObject().save();
excelWorkbook.saved(true);
excelApplication.quit();
Going this route worked well for me.