We have an application which accesses user's outlook account via the following code snippet (see the most upvoted answer): Reading e-mails from Outlook with Python through MAPI
import win32com.client
...
outlook = win32com.client.Dispatch("Outlook.Application").GetNamespace("MAPI")
It worked fine for several months, alas, a few days ago, it began to fail on all of the organization machines, while returning the following error: AttributeError: 'module' object has no attribute 'CLSIDToClassMap'
The source of the error is: WinPython-32bit-3.4.4.2\python-3.4.4\lib\site-packages\win32com\client\gencache.py
I suspect it's related to a security patch applied to Outlook. We use Office 2010 (Outlook 14.0.7173.500 32-bit)